| Group Main Use | Medication Brand/Generic |
Form | Dose Schedule | Dose Range | Most Common Side Effects for Group | Pros for Group | Cautions for Group |
| Remeron (depression booster) |
Remeron mirtazapine |
Tablet, Scored 15 mg 30 mg 45 mg Solutab 15, 30, 45mg |
Once a day, evening | Child:7.5-30 mg Adoles:7.5-45 mg Adult 15-45 mg |
Sedation, often increases appetite. May be less sedation at higher doses. | Less GI or sexual side effects than SRI group. Helps sleep, agitation and anxiety. Combination of Norepinephrine and serotonin boost. May boost other meds. Few interactions. No Routine labs or EKG. | Relatively new. Avoid combinations of overlap with MAOI. Same time onset as SRI or TCA. 3 Cases severe drop in white blood cell count during testing. All recovered when med stopped. |
| Wellbutrin (depression, booster, ADHD) |
Wellbutrin bupropion Zyban |
Tablet (not scored) 75 mg 100mg SR (slow release tablet, not scored) 100, 150, 200mg 150mg XL |
Given 2-3 times a
day. Start in the a.m. SR 1-2 times a day. |
Child:37.5-150mg Adoles:75-300mg Adult 150-450mg |
Increased energy. Decreased appetite. |
No significant sexual side
effects. No labs or EKG needed. Very few interactions. May help Attention Deficit Hyperactivity Disorder. Zyban form used to stop smoking. Good for boosting other meds. Side effects lessen with time Approved to help stop smoking. Generic available. |
Avoid if personal seizure
history. Caution if family seizure history. Avoid if bulimia. Must take 2
or 3 times daily. Probably less effective than SRI for severe anxiety.
Slow Release may be once or twice a day. Same time onset as SRI and TCA and all other antidepressants. |
| (depression sleep) |
Desyrel trazodone Oleptro trazodone XR Serzone nefazodone Savella milnacipran |
Tablets 50mg 100mg 150mg 300mg 150, 300mg XR
|
Usually bedtime
only Often twice a day
Usually twice a day |
Child: 25-200mg Adoles: 25-300mg Adult: 50-600mg Child:50-200mg Adoles:100-400mg Adult: 200-600mg 12.5 to 200mg 100mg is adult usual dose after building up slowly |
Sedation significant especially
with Trazodone. Dizziness. Sometimes also nausea with Serzone. Less Sedation and dizziness Like other SNRIs on page one. Can affect liver or urine flow. Nausea and constipation are most common. Little weight effect if any. |
Excellent sleep aid. Often used
to help sleep along with SRI or Wellbutrin. Not habit forming. No labs, EKG. Very low risk in overdose. No sexual side effects generally. May use as booster. Serzone brings benefit of different neurotransmitter effects. Although this is an SNRI like others on page 1 and approved in Europe for depression it's FDA approved so far only for Fibromyalgia. |
One in 10,000 risk of priapism.
Trazodone relatively weak antidepressant. Serzone may rarely damage the liver. Because it is an SNRI avoid use with an SRI or other SNRI. |
All these medications should be taken 7 days a week to be effective. Simultaneous use of alcohol or cigarettes and especially street drugs should be avoided. All antidepressants may increase mania risk in persons with Bipolar (manic-depressive) disorder. All medications should be avoided if possible in pregnancy. This chart is intended to be a summary guide, not a full and complete list.