Kevin Leehey, M.D.
1980 E. Ft. Lowell Road, Suite 150 • Tucson, Arizona 85719 • (520) 296-4280 • Fax: (520) 296-3835
MEDICATIONS FOR DEPRESSION, ANXIETY,
AND OBSESSIVE-COMPULSIVE DISORDER (Part 2)

Updated 1/07

Download PDF Version

 
Group Main Use Medication
Brand/Generic
Form Dose Schedule Dose Range Most Common Side Effects for Group Pros for Group Cautions for Group
Remeron
(depression booster)
Remeron
Mirtazapine
Tablet,
Scored
15 mg
30 mg
45 mg

Solutab
15, 30, 45mg
Once a day, evening Child:7.5-30 mg
Adoles:7.5-45 mg
Adult 15-45 mg
Sedation, often increases appetite. May be less sedation at higher doses. Less GI or sexual side effects than SRI group. Helps sleep, agitation and anxiety. Combination of Norepinephrine and serotonin boost. May boost other meds. Few interactions. No Routine labs or EKG. Relatively new. Avoid combinations of overlap with MAOI. Same time onset as SRI or TCA. 3 Cases severe drop in white blood cell count during testing. All recovered when med stopped.
Wellbutrin
(depression, booster, ADHD)
Wellbutrin
Bupropion
Zyban
Tablet
(not scored)
75 mg
100mg

SR (slow release tablet, not scored)
100, 150, 200mg

150mg XL
300mg XL

Given 2-3 times a day.
Start in the a.m.
SR 1-2 times a day.
Child:37.5-150mg
Adoles:75-300mg
Adult 150-450mg
Increased energy.
Decreased appetite.
No significant sexual side effects. No labs or EKG needed. Very few interactions.

May help Attention Deficit Hyperactivity Disorder. Zyban form used to stop smoking.

Good for boosting other meds. Side effects lessen with time

Approved to help stop smoking.

Generic available.
Avoid if personal seizure history. Caution if family seizure history. Avoid if bulimia. Must take 2 or 3 times daily. Probably less effective than SRI for severe anxiety. Slow Release may be once or twice a day.

Same time onset as SRI and TCA and all other antidepressants.
(depression
sleep)
Desyrel
Trazodone




Serzone
Nefazodone
Tablets
50mg
100mg
150mg
300mg

Tablets
100mg
150mg
200mg
250mg
Usually bedtime only




Often twice a day
Child: 25-200mg
Adoles: 25-300mg
Adult: 50-600mg



Child:50-200mg
Adoles:100-400mg
Adult: 200-600mg
Sedation significant especially with Trazodone. Dizziness.



Sometimes also nausea with Serzone. Less Sedation and dizziness
Excellent sleep aid. Often used to help sleep along with SRI or Wellbutrin. Not habit forming.

No labs, EKG. Very low risk in overdose. No sexual side effects generally. May use as booster.

Serzone brings benefit of different neurotransmitter effects.
One in 10,000 risk of priapism. Trazodone relatively weak antidepressant.


Serzone may rarely damage the liver.

All these medications should be taken 7 days a week to be effective. Simultaneous use of alcohol or cigarettes and especially street drugs should be avoided. All antidepressants may increase mania risk in persons with Bipolar (manic-depressive) disorder. All medications should be avoided if possible in pregnancy. This chart is intended to be a summary guide, not a full and complete list.

(dep2.html)