OLDER MEDICATIONS FOR DEPRESSION AND ANXIETY
Download PDF Version
|Group Main Use||Medication
|Form||Dose Schedule||Dose Range||Most Common Side Effects for Group||Pros for Group||Cautions for Group|
(depression, anxiety panic, migraines, sleep)
10, 25, 50, 75, 100, 150mg
|Usually once a day in the evening
Split dose may be useful (a.m. and p.m.)
Silenor is a brand of Doxepin for sleep that comes in only 3 and 6mg sizes.
|Child: 25-100 mg
Adoles: 50-150 mg
Blood levels may help guide dose.
Nortiptyline and Anafranil doses lower.
|Sedation, dry mouth, constipation. Dizziness, high heart rate, fatigue, blurry vision. May worsen abnormal heart rate or glaucoma or slow urination if enlarged prostrate. Occasional sexual side effects. Side-effects usually lessen with time.||Broad range of effects in
depression, panic attacks, sleep, pain, headaches, bed-wetting, ADHD, post
Does not cut appetite. Helps sleep.
Used to prevent migraines. Helps chronic pain. 50 years of well studied experience.
Vivactil is more likely to energize than other TCA's.
|Affects many transmitters so
relatively more side effects.
May be dangerous in overdose.
Labs and EKG usually advised to monitor heart, liver, and level in blood.
May increase appetite. Probably less effective than SRI for anxiety except panic.
25, 50, 100mg
Start 25 mg
2 to 3 times daily
2 or 3 times daily
|Evening||25-300 mg||Same as other TCA||May be the most effective medication for
obsessive-compulsive disorder (The only TCA that often helps due to also
having SRI action)
Children often tolerate better than adults.
|Same as other TCA although probably the most side effects, especially for adults.|
All these medications should be taken 7 days a week to be effective. Simultaneous use of alcohol or cigarettes and especially street drugs should be avoided. All antidepressants may increase mania risk in persons with Bipolar (manic-depressive) disorder. All medications should be avoided if possible in pregnancy. This chart is intended to be a summary guide, not a full and complete list.